Ayahuasca Retreat in Maine
There are places where the land itself becomes part of the medicine. Pachamama Sanctuary sits in the quiet forests of Casco, Maine — the original home of our community, where seekers have gathered for years to sit in ceremony, shed what no longer serves them, and return to themselves.
Our weekend retreats are grounded in Indigenous Amazonian tradition, held within a federally compliant, RFRA-protected church, and guided by teachers whose lineages and care you can trust.
Upcoming Ayahuasca Retreats In Maine
Ceremonies led by trained, lineage held teachers · Located in Casco, ME, 40 minutes from Portland
Sacred Ayahuasca Retreat with Johanka
September 4, 2026 - September 6, 2026
Filling Quickly
$947 | 3 Days, 2 Nights | Maine. Surrounded by the stillness of Maine’s lush forests, just outside of Portland, this Sacred Ayahuasca Retreat at Pachamama Sanctuary offers a deeply intentional space to pause, reset, and reconnect.
Sacred Ayahuasca Retreat with Arkawa
September 18, 2026 - September 20, 2026
Filling Quickly
$947 | 3 Days, 2 Nights | Maine We warmly welcome you into this sacred 3-day, 2-night immersion at Pachamama Sanctuary’s Ayahuasca Retreat outside of Portland, Maine.
Trusted by 5,000+ participants
About the Sanctuary

Pachamama Sanctuary in Casco, Maine is a sacred ceremonial space rooted in the Amazonian healing tradition of ayahuasca. Our retreats bring together small groups of seekers from Portland, Boston, New York, and beyond for weekend-long immersions that include two ayahuasca ceremonies, nourishing meals, breathwork, and integration practices held in a community of care.
The land holds the retreats as much as our teachers do. Casco’s forests of pine, birch, and quiet create a natural container for the inward journey. Participants often describe the setting as the first real silence they’ve found in years.
Whether you are arriving at your first ceremony or your fifteenth, you are welcomed here as you are.
Meet Your Hosts
Our Maine Team
The people who will guide, ground, and care for you throughout your weekend in Casco.
Derek
Founding Pastor
Misty
Guardian, Participant Screening & Safety Coordinator
Michelle
Guardian / Guest Experience
Glen
Retreat Director, Deacon
Angela
Deacon
Zoe
Culinary Lead

What to Expect at Our Maine Retreat
A Pachamama retreat weekend begins on Friday evening with arrival, an orientation circle, and a communal meal prepared with care. The first ceremony opens that night — held in a large ceremonial room where each participant rests on a prepared mattress, surrounded by candlelight and live medicine music.
The second ceremony takes place on Saturday evening. In the time between, participants rest, reflect, share in circle, and move through yoga, breathwork, or quiet time in the forest. Meals are prepared to support your body through the dieta, and the kitchen is always warm.
Sunday morning is for integration — group sharing, gentle guidance on carrying your insights home, and a closing ceremony of gratitude before departure.
Our facilitators and support team are present throughout the entire weekend, not just in ceremony.
Accommodations in Casco
Our accommodations are simple, warm, and intentional. Each participant is prepared a memory foam mattress — your ceremonial space for the weekend — along with clean linens, a blanket, and a pillow. For those who prefer more privacy, semi-private rooms with twin or full bunk beds are available for a peaceful place to sleep and decompress between ceremonies.

The space is designed to hold you gently. Hot water, clean bathrooms, a fire pit, and forest walks are all part of the journey.
Located at 50 Rabbit Run Lane, Casco, ME — approximately 40 minutes northwest of Portland.
Is ayahuasca legal in Maine at Pachamama Sanctuary?
Yes. Pachamama Sanctuary operates as a federally recognized religious church under the Religious Freedom Restoration Act (RFRA). Our sacramental use of ayahuasca is protected under federal law as an expression of sincere religious practice — a status we hold with deep responsibility.
Before every retreat, each participant completes a thorough medical and psychological intake. Our guidelines exist to protect you. Participants with certain medications or medical histories may be asked to postpone their journey, and we take that seriously. Your safety is the foundation upon which the ceremony is built.
Our facilitators are experienced, trained in ceremonial protocol, and hold their lineages with integrity. Integration support continues after you leave — because the ceremony does not end when you return home.
FAQ
How do I get to the Casco retreat center?
Our sanctuary is located at 50 Rabbit Run Lane, Casco, ME 04015 — approximately 40 minutes northwest of Portland.
Is this retreat right for first-timers?
Yes. Most of our participants are coming to ceremony for the first time. Our facilitators are experienced at holding beginners, and your full weekend includes preparation, integration, and ongoing post-retreat support.
What does an ayahuasca ceremony involve?
Ceremony takes place in the evening and lasts several hours. You rest on a prepared mattress while facilitators guide the space through music, song, and presence. The experience varies for each person — some find clarity, some face difficulty, many experience both. You are never alone in the room.
What should I bring?
omfortable clothes for ceremony, layers for the Maine evenings, any personal comfort items, and a journal. A full packing guide is sent with your booking.
How much does the retreat cost?
Weekend includes ceremonies, accommodations, and all meals. Pricing may vary by retreat to view our current prices visit our upcoming retreat page. No hidden fees.
What is the diet/dieta and do I have to follow it?
The diet is a period of dietary and lifestyle preparation before ceremony that supports your body and opens your receptivity to the medicine. We ask all participants to follow our guidelines in the week before arrival.
What happens after the retreat?
Integration is part of the path. All participants are invited to our weekly Tuesday Integration Circle at 7 PM EST, where the community gathers to share, reflect, and support one another in carrying ceremony insights into daily life.
How do I book a retreat in Maine?
Browse upcoming Maine dates and reserve your seat directly on our website. Retreats fill weeks in advance — early registration is encouraged.
Ready to begin your journey?
The forest is waiting. Retreats in Casco, Maine fill weeks in advance — seats are limited by design so that every participant is held with genuine care.
View Upcoming Maine Retreat DatesHave questions before committing? We answer every message personally.
Get in Touch with Our Team